Hydrocephalus is a devastating structural neurological disorder marked by enlarged brain ventricles due to accumulation of cerebrospinal fluid. The current diagnosis and treatment of hydrocephalus is inadequate due to a lack of understanding about the mechanisms behind its development. Hydrocephalus may be accompanied by low intracranial pressure and it continues to remain a clinical challenge to differentiate this disease with […]
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Dr James Burrell is a Senior Research Officer and clinical neurologist whose research interests lie in linking clinical symptoms and pathology in dementia syndromes. In my work as a clinical neurologist, I often encounter people who are concerned that they might be developing the dreaded d-word: dementia. They report being more forgetful than previously, forgetting the names of people, places […]
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Over the past few decades, the neuroscience community has seen a huge growth in new types of experiments, and methods for analysing data. But there is no magic wand for data analysis: having a large, flexible toolbox of methods can accidentally lead to the equivalent of baking a cake using salt instead of sugar: the ingredients look sensible and might […]
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Life is full of things that are not necessarily what they seem to be, and the same applies when diseases mimic each other and make diagnosis difficult. This is particularly true for different dementias, which often show similar and overlapping symptoms.
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Evolution is the gradual development of something into a more complex or better form. I witness this everyday as a paediatric neurologist: A newborn is vulnerable and fully dependent on its parents and during childhood movements become smooth and an infant learns to stand, walk and then run. Compared to development in other species, human children take a long time […]
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