Category Archives: Dementia

Could immunological mechanisms trigger neurodegeneration in frontotemporal dementia?

Frontotemporal dementia (FTD)  is the second most common degenerative disease causing dementia in younger adults, with onset typically occurring in the 50s or 60s. In FTD, damage to brain cells begins in the frontal and/or temporal lobes of the brain, which often results in personality and behavioural changes or losing the ability to speak or understand language. When conveying a […]

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Bringing words back

You know the word…it’s right there…on the tip of your tongue…and…it’s gone again. Argh! Struggling to think of a certain word is something everyone encounters. For a specific group of dementia patients, however, this is a daily battle and often involves words for common household objects previously well remembered (e.g kettle). Semantic dementia is a disease that attacks language in […]

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Alzheimer’s disease and logopenic aphasia: Two faces of the same coin.

Getting lost in shopping malls, leaving doors unlocked and difficulty remembering what you ate last night are situations that caregivers and patients with Alzheimer’s disease know well and have to deal with every day. Yet, what would you think, if instead of getting lost, someone had trouble finding the right word? Would you still call this Alzheimer’s disease?

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The people behind DIAN

This month we have sent out an appeal letter in which Chontell Johnson tells her story. Chontell’s mother had the genetic form of Alzheimer’s disease and Chontell made the decision to have predictive testing some years ago. She found out that she carries the form of the gene responsible for causing Alzheimer’s disease in her family. Other family members have […]

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How does having dementia affect everyday activities?

A NeuRA study recently investigated how different types of dementia affect the ability to perform everyday tasks. The focus was on progressive nonfluent aphasia (PNFA) and logopenic nonfluent aphasia (LPA) – two dementias that lead to similar problems in language (at least to the untrained ear, not so according to specific language tests). Under the microscope these dementias look very different: […]

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Musical cognition: the demise of ‘left-brain right-brain’?

When looking at a human face we take it for granted that we can distinguish a happy face from a sad face and a scary face from a relaxed face. People with Alzheimer’s disease and other dementias often exhibit deficits in this area, and while this is interesting from a cognitive perspective, it has real world implications for the families of people […]

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